A US team were trying to explain why some tissues were millions of times more vulnerable to cancer than others.
The results, in the journal Science, showed two thirds of the cancer types analysed were caused just by chance mutations rather than lifestyle.
However some of the most common and deadly cancers are still heavily influenced by lifestyle.
And Cancer Research UK said a healthy lifestyle would still heavily stack the odds in a person's favour.
So is it time to light-up, drink and eat what you want without a care in the world?
It won't come as a surprise that the answer is no.
All cancer has an element of chance - a roll of the dice that decides whether your DNA acquires a mutation that leads to cancer.
The study shows that
two thirds of cancer types are simply chance.
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